Spheronization

The Spheronization Process

Spheronization is a rapid and flexible manufacturing process that creates small spheres or spheroids for pharmaceutical products. Spheronized products are dense with a uniform size and shape with a defined surface.

The Spheronization Process

 

  • Powder mix of ingredients/ Formula creation
  • Formula converted into a plastic mass
  • Extruded and processed through a spheronizer
  • Spheres are then dried and coated
  • Produces a perfectly round, hard, and smooth sphere

FEATURES:

  • Approximately 0.6 to 3 mm in diameter
  • High level of active ingredients in each sphere
  • Rapid and flexible manufacturing process
  • Dense with uniform shape
  • Customizable ingredients, colors, and formulas
  • Specific time release properties
  • Enteric coating
  • Mixing of incompatible ingredients
  • Dust elimination
  • Spheres can be combined into a capsule or tablet
  • High volume capacity
  • ¬†Product differentiation

BENEFITS OF ENTERIC COATING:

  • Blocks oxidation
  • Blocks moisture
  • Eliminates taste
  • Eliminates odor
  • Protects the sphere from ambient heat
  • Keeps the product intact during transport, storage, and display
  • Controls the release of the formula:
    • Immediate
    • Delayed
    • Sustained
    • Compounded

Use your own ingredients or choose from our list of AVAILABLE PRODUCTS:

  • Alpha Lipoic Acid
  • Caffeine
  • Calcium
  • Capsaicin
  • Capsicum
  • Folic Acid
  • L-Theanine
  • Lutein
  • Melatonin
  • N-Acetylcysteine
  • Niacinamide
  • Riboflavin
  • Selenium
  • Thiamine
  • Vitamin A
  • Vitamin B6
  • Vitamin B12
  • Vitamin C
  • Vitamin D3
  • Vitamin E
  • Zinc